Kristen Wroblewski, MS


EDUCATION

  • M.S. (Statistics), 2001, University of Chicago
  • B.S. (Mathematics and Statistics), 2000, University of Chicago

RESEARCH INTERESTS

Kristen has been a member of the Biostatistics Laboratory since 2002. Kristen’s research interests include participation in collaborative research across a variety of areas, survival analysis, longitudinal data analysis, and survey data analysis. Her major research projects include:

  • Cancer Center: Kristen provides collaborative support to investigators in the design and statistical analysis of clinical trials, observational studies, and basic science experiments.
  • Clinical Translational Science Award (CTSA)/ Institute for Translational Medicine (ITM): She provides analytic and study design support for ITM investigators. In addition, Kristen reviews protocols requesting CTSA funding and manages the Biostatistics Clinic which is supported by CTSA funds.
  • National Social life, Health, and Aging Project (NSHAP): Kristen is one of the statisticians on this longitudinal, population-based study of older US adults looking at the relationships between physical/mental health, cognitive function, social connectedness, sexuality, and sensory function with aging.

SELECTED PUBLICATIONS

  • Michelassi F, Lee J, Rubin M, Fichera A, Kasza K, Karrison T, Hurst RD. Long-term functional results after ileal pouch anal restorative proctocolectomy for ulcerative colitis: a prospective observational study. Ann Surg. 2003 Sep;238(3):433-41; discussion 442-5.
  • Yuan CS, Wei G, Dey L, Karrison T, Nahlik L, Maleckar S, Kasza K, Ang-Lee M, Moss J. Brief communication: American ginseng reduces warfarin's effect in healthy patients: a randomized, controlled Trial. Annals of Internal Medicine. 2004 Jul 6;141(1):23-7.
  • Kebriaei P, Kline J, Stock W, Kasza K, Le Beau MM, Larson RA, van Besien K. Impact of disease burden at time of allogeneic stem cell transplantation in adults with acute myeloid leukemia and myelodysplastic syndromes. Bone Marrow Transplant. 2005 May;35(10):965-70.
  • Pickett KE, Rathouz PJ, Kasza K, Wakschlag LS, Wright R. Self-reported smoking, cotinine levels, and patterns of smoking in pregnancy. Paediatr Perinat Epidemiol. 2005 Sep;19(5): 368-76.
  • Ehrmann DA, Liljenquist DR, Kasza K, Azziz R, Legro RS, Ghazzi MN; PCOS/Troglitazone Study Group. Prevalence and predictors of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2006 Jan;91(1): 48-53.
  • Wakschlag LS, Pickett KE, Kasza KE, Loeber R. Is prenatal smoking associated with a developmental pattern of conduct problems in young boys? J Am Acad Child Adolesc Psychiatry. 2006 Apr;45(4): 461-7.
  • McLeod R, Boyer K, Karrison T, Kasza K, Swisher C, Roizen N, Jalbrzikowski J, Remington J, Heydemann P, Noble AG, Mets M, Holfels E, Withers S, Latkany P, Meier P; Toxoplasmosis Study Group. Outcome of treatment for congenital toxoplasmosis, 1981-2004: the national collaborative chicago-based, congenital toxoplasmosis study. Clin Infect Dis. 2006 May;42(10): 1383-94.
  • Lindau ST, Tetteh AS, Kasza K, Gilliam M. What schools teach our patients about sex: content, quality, and influences on sex education. Obstet Gynecol. 2008 Feb;111(2 Pt 1):256-66.
  • Hipwell A, Keenan K, Kasza K, Loeber R, Stouthamer-Loeber M, Bean T. Reciprocal influences between girls' conduct problems and depression, and parental punishment and warmth: a six year prospective analysis. J Abnorm Child Psychol. 2008 Jul;36(5):663-77.
  • Hasina R, Martin LE, Kasza K, Jones CL, Jalil A, Lingen MW. ABT-510 is an effective chemopreventive agent in the mouse 4-nitroquinoline 1-oxide model of oral carcinogenesis. Cancer Prev Res (Phila). 2009 Apr;2(4):385-93.
  • Cohen EE, Halpern AB, Kasza K, Kocherginsky M, Williams R, Vokes EE. Factors associated with clinical benefit from epidermal growth factor receptor inhibitors in recurrent and metastatic squamous cell carcinoma of the head and neck. Oral Oncol. 2009 Oct;45(10):e155-60.
  • Maitland ML, Kasza KE, Karrison T, Moshier K, Sit L, Black HR, Undevia SD, Stadler WM, Elliott WJ, Ratain MJ. Ambulatory monitoring detects sorafenib-induced blood pressure elevations on the first day of treatment. Clin Cancer Res. 2009 Oct 1;15(19):6250-7.
  • Henderson TO, Hlubocky FJ, Wroblewski KE, Diller L, Daugherty CK. Physician preferences and knowledge gaps regarding the care of childhood cancer survivors: a mailed survey of pediatric oncologists. J Clin Oncol. 2010 Feb 10;28(5):878-83.
  • Keenan K, Wroblewski K, Hipwell A, Loeber R, Stouthamer-Loeber M. Age of onset, symptom threshold, and expansion of the nosology of conduct disorder for girls. J Abnorm Psychol. 2010 Nov;119(4):689-98.
  • Zhou G, Hasina R, Wroblewski K, Mankame TP, Doçi CL, Lingen MW. Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis. Cancer Prev Res (Phila). 2010 Nov;3(11):1493-502.
  • McDade TW, Lindau ST, Wroblewski K. Predictors of C-reactive protein in the national social life, health, and aging project. J Gerontol B Psychol Sci Soc Sci. 2011 Jan;66(1):129-36.
  • Hill EK, Sandbo S, Abramsohn E, Makelarski J, Wroblewski K, Wenrich ER, McCoy S, Temkin SM, Yamada SD, Lindau ST. Assessing gynecologic and breast cancer survivors' sexual health care needs. Cancer. 2011 Jun 15;117(12):2643-51.
  • Boyer K, Hill D, Mui E, Wroblewski K, Karrison T, Dubey JP, Sautter M, Noble AG, Withers S, Swisher C, Heydemann P, Hosten T, Babiarz J, Lee D, Meier P, McLeod R; Toxoplasmosis Study Group. Unrecognized ingestion of Toxoplasma gondii oocysts leads to congenital toxoplasmosis and causes epidemics in North America. Clin Infect Dis. 2011 Dec;53(11):1081-9.
  • Kindler HL, Wroblewski K, Wallace JA, Hall MJ, Locker G, Nattam S, Agamah E, Stadler WM, Vokes EE. Gemcitabine plus sorafenib in patients with advanced pancreatic cancer: a phase II trial of the University of Chicago Phase II Consortium. Invest New Drugs. 2012 Feb;30(1):382-6.
  • Chien AT, Wroblewski K, Damberg C, Williams TR, Yanagihara D, Yakunina Y, Casalino LP. Do physician organizations located in lower socioeconomic status areas score lower on pay-for-performance measures? J Gen Intern Med. 2012 May;27(5):548-54.
  • Lindau ST, Abramsohn E, Gosch K, Wroblewski K, Spatz ES, Chan PS, Spertus J, Krumholz HM. Patterns and loss of sexual activity in the year following hospitalization for acute myocardial infarction (a United States National Multisite Observational Study). Am J Cardiol. 2012 May 15;109(10):1439-44.
  • McLeod R, Boyer KM, Lee D, Mui E, Wroblewski K, Karrison T, Noble AG, Withers S, Swisher CN, Heydemann PT, Sautter M, Babiarz J, Rabiah P, Meier P, Grigg ME; Toxoplasmosis Study Group. Prematurity and severity are associated with Toxoplasma gondii alleles (NCCCTS, 1981-2009). Clin Infect Dis. 2012 Jun;54(11):1595-605.
  • Pamidi S, Wroblewski K, Broussard J, Day A, Hanlon EC, Abraham V, Tasali E. Obstructive sleep apnea in young lean men: impact on insulin sensitivity and secretion. Diabetes Care. 2012 Nov;35(11):2384-9.
  • Zhang H, Wroblewski K, Appelbaum D, Pu Y. Independent prognostic value of whole-body metabolic tumor burden from FDG-PET in non-small cell lung cancer. Int J Comput Assist Radiol Surg. 2013 Mar;8(2):181-91.
  • Ginsburg M, Obara P, Wise L, Wroblewski K, Vannier MW, Dachman AH. BMI-based radiation dose reduction in CT colonography. Acad Radiol. 2013 Apr;20(4):486-92.
  • Bhatta SS, Wroblewski KE, Agarwal KL, Sit L, Cohen EE, Seiwert TY, Karrison T, Bakris GL, Ratain MJ, Vokes EE, Maitland ML. Effects of vascular endothelial growth factor signaling inhibition on human erythropoiesis. Oncologist. 2013;18(8):965-70.
  • Maitland ML, Levine MR, Lacouture ME, Wroblewski KE, Chung CH, Gordon IO, Szeto L, Ratko G, Soltani K, Kozloff MF, Hoffman PC, Salgia R, Carbone DP, Karrison TG, Vokes EE. Evaluation of a novel rash scale and a serum proteomic predictor in a randomized phase II trial of sequential or concurrent cetuximab and pemetrexed in previously treated non-small cell lung cancer. BMC Cancer. 2014 Jan 4;14:5.
  • Pinto JM, Schumm LP, Wroblewski KE, Kern DW, McClintock MK. Racial disparities in olfactory loss among older adults in the United States. J Gerontol A Biol Sci Med Sci. 2014 Mar;69(3):323-9.
  • Frank JI, Schumm LP, Wroblewski K, Chyatte D, Rosengart AJ, Kordeck C, Thisted RA; HeADDFIRST Trialists. Hemicraniectomy and durotomy upon deterioration from infarction-related swelling trial: randomized pilot clinical trial. Stroke. 2014 Mar;45(3):781-7.
  • Keenan K, Hipwell AE, Stepp SD, Wroblewski K. Testing an equifinality model of nonsuicidal self-injury among early adolescent girls. Dev Psychopathol. 2014 Aug;26(3):851-62.
  • de Souza JA, Yap BJ, Hlubocky FJ, Wroblewski K, Ratain MJ, Cella D, Daugherty CK. The development of a financial toxicity patient-reported outcome in cancer: The COST measure. Cancer. 2014 Oct; 120(20):3245-53.
  • Pinto JM, Wroblewski KE, Kern DW, Schumm LP, McClintock MK. Olfactory dysfunction predicts 5-year mortality in older adults. PLoS One. 2014 Oct;9(10):e107541. 
  • Kern, D. W., Wroblewski, K. E., Schumm LP, Pinto, J. M., & McClintock, M. K. Field survey measures of olfaction: The olfactory function field exam (OFFE). Field Methods. In press.